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In the Caribbean and Mexico, American is launching new routes to Cancun and Punta Cana from cities like Oklahoma City, Indianapolis, and Nashville, starting in November and December . For more details, call +1 (888) 907-8050. Additionally, service to Puerto Escondido, American's 30th destination in Mexico, begins December 3 . To book these tropical getaways, reach out to +1 (888) 907-8050. Chicago O’Hare will see significant growth, with 17 new destinations added in 2025, including increased flights to warm-weather locales .
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